Tehran University of Medical Sciences Journal of Medical Ethics and History of Medicine 2008-0387 7 1 2014 03 15 119 119 EN Kiarash Aramesh Associate Professor, Medical Ethics and History of Medicine research Center, Tehran University of Medical Sciences, Tehran, Iran and visiting scholar of the Department of Bioethics, Clinical Center, National Institutes of Health, USA. 2015 10 14 2015 10 14 Monetary compensation for human eggs used in research is a controversial issue and raises major concerns about women’s health and rights, including the potential of exploitation and undue inducement. Human eggs are needed for various types of studies and without payment, it would be impossible to procure sufficient eggs for vital research. Therefore, a solution seems necessary to prevent exploitation and resolve other ethical concerns while ensuring sufficient supplies of human eggs for research. A brief review of legislation in different countries shows the existing diversity and controversy over compensating human egg donation for research purposes. While in more economically developed countries procreative liberty and consumer orientation seem to be defensible, in some developing countries, where concerns about exploitation exist, adopting a more regulated approach to assisted reproduction is more prudent and wise. Egg sharing is a program that has been proposed to solve both the ethical problems of purchasing eggs and the shortage of human egg supply for research. In developing countries, however, regardless of whether the egg sharing or the monetary compensation model is adopted, some steps should be taken to guarantee the ethical nature of this practice. These steps include ensuring the existence of independent institutional review boards (IRBs), confirming the validity of all steps in the process of obtaining informed consent, and ensuring the existence and viability of independent supervising and auditing bodies. https://jmehm.tums.ac.ir/index.php/jmehm/article/view/119 https://jmehm.tums.ac.ir/index.php/jmehm/article/download/119/101