The relationship between human dignity and medication adherence in patients with heart failure
Abstract
Medication adherence is a behavior that is influenced by several factors, and maintaining patients’ dignity is an important issue that needs to be considered in the course of treatment. The present study aimed to determine the relationship between human dignity and medication adherence in patients with heart failure. This was a cross-sectional study. A total number of 300 patients with heart failure admitted to the Mazandaran Heart Center, Iran, participated in this study by census. Samples were selected based on inclusion criteria such as an HF diagnosis by a cardiologist for a minimum of 6 months, and taking at least one cardiac medication. Data were collected through demographic, clinical, human dignity, and medication adherence questionnaires over a period of three months in 2016. This study was approved by the Ethics Committee of Mazandaran University of Medical Sciences. Consents were obtained from patients and the medical center, and necessary explanations were given about the confidentiality of information prior to completing the questionnaires. The mean score of medication adherence was 5.82 suggesting low medication adherence among the patients, and the mean score of human dignity was 81.39. There was a negative relationship between medication adherence and threat to human dignity (r = - 0.6, P < 0.001), i.e., the higher the scores of threat, the lower the medication adherence of the patients. After adjusting the effects of potential confounding variables, there still was a correlation between medication adherence and the variables of human dignity and its dimensions. Based on the findings, an increase in patients’ dignity can enhance medication adherence, which can theoretically improve patients’ health and reduce frequent hospitalization.
1. McMurray JJ, Adamopoulos S, Anker SD, et al. ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure 2012: the task force for the diagnosis and treatment of acute and chronic heart failure 2012 of the European Society of Cardiology developed in collaboration with the Heart Failure Association (HFA) of the ESC. Eur J Heart Fail. 2012; 14(8): 803-69.
2. Wu J-R, Moser DK, Lennie TA, Peden AR, Chen YC, Heo S. Factors influencing medication adherence in patients with heart failure. Heart Lung. 2008; 37(1): 8-16.
3. Ruppar TM, Delgado JM, Temple J. Medication adherence interventions for heart failure patients: a meta-analysis. Europ J Cardiovasc Nurs. 2015; 22(2): 54-63.
4. Bagheri H, Yaghmaei F, Ashktorab T, Zayeri F. Patient dignity and its related factors in heart failure patients. Nurs Ethics. 2012; 3(1): 316-27.
5. Heydari A, Ahrari S, Vaghee S. The relationship between self-concept and adherence to therapeutic regimens in patients with heart failure. J Cardiovasc Nurs. 2011; 26(6): 475-80.
6. Masror Roudsari D, Dabiri Golchin M, Parsa yekta Z, Haghani H. Relationship between adherence to therapeutic regimen and health related quality of life in hypertensive patients. Iran Journal of Nursing. 2013; 26(85): 44-54. [in Persian]
7. Choudhry NK, Shrank WH, Levin RL, et al. Measuring concurrent adherence to multiple related medications. Am J Manag Care. 2009; 15(7): 457-64.
8. Brown MT, Bussell JK. Medication adherence: WHO cares? Mayo Clinic Proc. 2011; 86(4): 304-14.
9. Hawkins LA, Kilian S, Firek A, Kashner TM, Firek CJ, Silvet H. Cognitive impairment and medication adherence in outpatients with heart failure. Heart Lung. 2012; 41(6): 572-82.
10. Berben L, Bogert L, Leventhal ME, et al. Which interventions are used by health care professionals to enhance medication adherence in cardiovascular patients? a survey of current clinical practice. Eur J Cardiovasc Nurs. 2011; 10(1): 14-21.
11. Campbell NL, Boustani MA, Skopelja EN, Gao S, Unverzagt FW, Murray MD. Medication adherence in older adults with cognitive impairment: a systematic evidence-based review. Am J Geriatr Pharmacother. 2012; 10(3): 165-77.
12. Molloy GJ, O'Carroll RE, Witham MD, McMurdo ME. Interventions to enhance adherence to medications in patients with heart failure a systematic review. Circ Heart Fail. 2012; 5(1): 126-33.
13. Jacobs Ú, De Castro MS, Fuchs FD, Ferreira MBC. The influence of cognition, anxiety and psychiatric disorders over treatment adherence in uncontrolled hypertensive patients. PloS One. 2011; 6(8): e22925.
14. Dehghan Nayeri N, Karimi R, Sadeghee T. Iranian nurses and hospitalized teenagers’ views of dignity. Nurs Ethics. 2011; 18(4): 474-84.
15. Lin Y-P, Watson R, Tsai Y-F. Dignity in care in the clinical setting: a narrative review. Nurs Ethics. 2013; 20(2): 165-77.
16. Lam KK. Dignity, respect for dignity, and dignity conserving in palliative care. HKSPM Newsletter. 2007; 3: 30-5.
17. Matiti MR, Trorey GM. Patients’ expectations of the maintenance of their dignity. J Clin Nurs. 2008; 17(20):2709-17.
18. Jacobson N. Dignity and health: a review. Soc Sci Med. 2007; 64(2): 292-302.
19. Bagheri H, Yaghmaei F, Ashktorab T, Zayeri F. Development and psychometric properties of Inherent Dignity Questionnaire in heart failure patients. J Med Ethics Hist Med. 2014; 6(6):33-44.
20. Maeda U, Shen B-J, Schwarz ER, Farrell KA, Mallon S. Self-efficacy mediates the associations of social support and depression with treatment adherence in heart failure patients. Int J Behav Med. 2013; 20(1):88-96.
21. Macabasco-O’Connell A, DeWalt DA, Broucksou KA, et al. Relationship between literacy, knowledge, self-care behaviors, and heart failure-related quality of life among patients with heart failure. J Gen InternI Med. 2011; 26(9):979-86.
22. Ratanawongsa N, Karter AJ, Parker MM, et al. Communication and medication refill adherence: the Diabetes study of Northern California. JAMA Intern Med. 2013; 173(3):210-8.
23. Fahlberg B. Promoting patient dignity in nursing care. Nursing. 2014; 44(7):14.
24. Baljani MS, Zh. Rahimi MS, Sh. Heidari MS, A. Azimpour MS. The Effect of self-management interventions on medication adherence and life style in cardiovascular patients. Nasim-Danesh. 2013; 20(3):58-68.
25. Heydari A, Ziaee ES, Gazrani A. Relationship between awareness of disease and adherence to therapeutic regimen among cardiac patients. Int J Community Based Nurs Midwifery. 2015; 3(1):23-30.
26. Noureldin M, Plake KS, Morrow DG, Tu W, Wu J, Murray MD. Effect of health literacy on drug adherence in patients with heart failure. Pharmacotherapy. 2012; 32(9):819-26.
27. Dias A, Pereira C, Monteiro MJ, Santos C. Patients’ beliefs about medicines and adherence to medication in ischemic heart disease. Aten Primaria. 2014; 46:101-6.
28. Chochinov HM, Hassard T, McClement S, et al. The patient dignity inventory: a novel way of measuring dignity-related distress in palliative care. J Pain Symptom Manage. 2008; 36(6):559-71.
29. Abbaszadeh A, Borhani F, Rabori R. Patient dignity in coronary care: psychometrics of the Persian version of the patient dignity inventory. British Journal of Medicine and Medical Research. 2015; 8(5):463-9.
30. Morisky DE, Ang A, Krousel‐Wood M, Ward HJ. Predictive validity of a medication adherence measure in an outpatient setting. J Clin Hyperten. 2008; 10(5):348-54
31. Rashedi E, Sohrabi F, Shams J. A study of the efficacy of cognitive behavior therapy in replace prevention of bipolar disorder. Clinical Psychology & Personality. 2011; 2(5):49-64.
32. Alosco ML, Spitznagel MB, van Dulmen M, et al. Cognitive function and treatment adherence in older adults with heart failure. Psychosom Med. 2012; 74(9):965-73.
33. Gehi AK, Ali S, Na B, Whooley MA. Self-reported medication adherence and cardiovascular events in patients with stable coronary heart disease: the heart and soul study. Arch Internal Med. 2007; 167(16):1798-803.
34. van der Wal MH, Jaarsma T, Moser DK, Veeger NJ, van Gilst WH, van Veldhuisen DJ. Compliance in heart failure patients: the importance of knowledge and beliefs. Eur Heart J. 2006; 27(4):434-40.
35. Schweitzer RD, Head K, Dwyer JW. Psychological factors and treatment adherence behavior in patients with chronic heart failure. J Cardiovasc Nurs. 2007; 22(1):76-83.
36. Grenard JL, Munjas BA, Adams JL, et al. Depression and medication adherence in the treatment of chronic diseases in the United States: a meta-analysis. J Gen Intern med. 2011; 26(10):1175-82.
37. Ebrahimzadeh Z, Goodarzi MA, Joulaei H. The Clarification of depression and social support's contribution to the prediction of antiretroviral medication adherence and the rate of CD4 in people with HIV. Glob J Health Sci. 2016; 8(9):54842.
38. Adewuya AO, Afolabi MO, Ola BA, et al. The effect of psychological distress on medication adherence in persons with HIV infection in Nigeria. Psychosomatics. 2010; 51(1):68-73.
39. Chen H-F, Tsai Y-F, Lin Y-P, Shih M-S, Chen J-C. The relationships among medicine symptom distress, self-efficacy, patient–provider relationship, and medication compliance in patients with epilepsy. Epilepsy Behav. 2010; 19(1):43-9.
40. King MLM, Mee LL, Gutiérrez-Colina AM, Eaton CK, Lee JL, Blount RL. Emotional functioning, barriers, and medication adherence in pediatric transplant recipients. J Pediatr Psychol. 2014; 39(3):283-93.
41. Gonzalez JS, Shreck E, Psaros C, Safren SA. Distress and type 2 diabetes-treatment adherence: a mediating role for perceived control. Health Psychol. 2015; 34(5):505.
42. Senior V, Marteau TM, Weinman J. Self-reported adherence to cholesterol-lowering medication in patients with familial hypercholesterolaemia: the role of illness perceptions. Cardiovasc Drugs Ther. 2004; 18(6):475-81.
43. Kretchy I, Owusu-Daaku F, Danquah S. Spiritual and religious beliefs: do they matter in the medication adherence behaviour of hypertensive patients? Biopsychosoc Med. 2013; 7(1):15.
44. Criswell TJ, Weber CA, Xu Y, Carter BL. Effect of self‐efficacy and social support on adherence to antihypertensive drugs. Pharmacotherapy. 2010; 30(5):432-41.
45. Gonzalez JS, Penedo FJ, Antoni MH, et al. Social support, positive states of mind, and HIV treatment adherence in men and women living with HIV/AIDS. Health Psychol. 2004; 23(4):413.
46. Rueda S, Park‐Wyllie LY, Bayoumi A, et al. Patient support and education for promoting adherence to highly active antiretroviral therapy for HIV/AIDS. Cochrane Database Syst Rev. 2006; 12(4):325-34.
47. Edwards LV. Perceived social support and HIV/AIDS medication adherence among African American women. Qual Health Res. 2006; 16(5):679-91.
48. Simoni JM, Frick PA, Huang B. A longitudinal evaluation of a social support model of medication adherence among HIV-positive men and women on antiretroviral therapy. Health Psychol. 2006; 25(1):74-81.
49. Scheurer D, Choudhry N, Swanton KA, Matlin O, Shrank W. Association between different types of social support and medication adherence. Am J Manag Care. 2012; 18(12):e461-7.
50. Wu J-R, Moser DK, Lennie TA, Burkhart PV. Medication adherence in patients who have heart failure: a review of the literature. Nurs Clin North Am. 2008; 43(1):133-53.
51. Sayers SL, Riegel B, Pawlowski S, Coyne JC, Samaha FF. Social support and self-care of patients with heart failure. Ann Behav Med. 2008; 35(1):70-9.
52. Takedai T. The association between social support and medication adherence in adults with rheumatoid arthritis [dissertation]. Pittsburgh (USA). University of Pittsburgh; 2016.
53. Vyavaharkar M, Moneyham L, Tavakoli A, et al. Social support, coping, and medication adherence among HIV-positive women with depression living in rural areas of the southeastern United States. AIDS Patient Care a STDS. 2007; 21(9):667-80.
54. Beals K, Wight R, Aneshensel C, Murphy D, Miller-Martinez D. The role of family caregivers in HIV medication adherence. AIDS care. 2006; 18(6):589-96.
55. Stilley CS, Bender CM, Dunbar-Jacob J, Sereika S, Ryan CM. The impact of cognitive function on medication management: three studies. Health Psychol. 2010; 29(1):50-5.
2. Wu J-R, Moser DK, Lennie TA, Peden AR, Chen YC, Heo S. Factors influencing medication adherence in patients with heart failure. Heart Lung. 2008; 37(1): 8-16.
3. Ruppar TM, Delgado JM, Temple J. Medication adherence interventions for heart failure patients: a meta-analysis. Europ J Cardiovasc Nurs. 2015; 22(2): 54-63.
4. Bagheri H, Yaghmaei F, Ashktorab T, Zayeri F. Patient dignity and its related factors in heart failure patients. Nurs Ethics. 2012; 3(1): 316-27.
5. Heydari A, Ahrari S, Vaghee S. The relationship between self-concept and adherence to therapeutic regimens in patients with heart failure. J Cardiovasc Nurs. 2011; 26(6): 475-80.
6. Masror Roudsari D, Dabiri Golchin M, Parsa yekta Z, Haghani H. Relationship between adherence to therapeutic regimen and health related quality of life in hypertensive patients. Iran Journal of Nursing. 2013; 26(85): 44-54. [in Persian]
7. Choudhry NK, Shrank WH, Levin RL, et al. Measuring concurrent adherence to multiple related medications. Am J Manag Care. 2009; 15(7): 457-64.
8. Brown MT, Bussell JK. Medication adherence: WHO cares? Mayo Clinic Proc. 2011; 86(4): 304-14.
9. Hawkins LA, Kilian S, Firek A, Kashner TM, Firek CJ, Silvet H. Cognitive impairment and medication adherence in outpatients with heart failure. Heart Lung. 2012; 41(6): 572-82.
10. Berben L, Bogert L, Leventhal ME, et al. Which interventions are used by health care professionals to enhance medication adherence in cardiovascular patients? a survey of current clinical practice. Eur J Cardiovasc Nurs. 2011; 10(1): 14-21.
11. Campbell NL, Boustani MA, Skopelja EN, Gao S, Unverzagt FW, Murray MD. Medication adherence in older adults with cognitive impairment: a systematic evidence-based review. Am J Geriatr Pharmacother. 2012; 10(3): 165-77.
12. Molloy GJ, O'Carroll RE, Witham MD, McMurdo ME. Interventions to enhance adherence to medications in patients with heart failure a systematic review. Circ Heart Fail. 2012; 5(1): 126-33.
13. Jacobs Ú, De Castro MS, Fuchs FD, Ferreira MBC. The influence of cognition, anxiety and psychiatric disorders over treatment adherence in uncontrolled hypertensive patients. PloS One. 2011; 6(8): e22925.
14. Dehghan Nayeri N, Karimi R, Sadeghee T. Iranian nurses and hospitalized teenagers’ views of dignity. Nurs Ethics. 2011; 18(4): 474-84.
15. Lin Y-P, Watson R, Tsai Y-F. Dignity in care in the clinical setting: a narrative review. Nurs Ethics. 2013; 20(2): 165-77.
16. Lam KK. Dignity, respect for dignity, and dignity conserving in palliative care. HKSPM Newsletter. 2007; 3: 30-5.
17. Matiti MR, Trorey GM. Patients’ expectations of the maintenance of their dignity. J Clin Nurs. 2008; 17(20):2709-17.
18. Jacobson N. Dignity and health: a review. Soc Sci Med. 2007; 64(2): 292-302.
19. Bagheri H, Yaghmaei F, Ashktorab T, Zayeri F. Development and psychometric properties of Inherent Dignity Questionnaire in heart failure patients. J Med Ethics Hist Med. 2014; 6(6):33-44.
20. Maeda U, Shen B-J, Schwarz ER, Farrell KA, Mallon S. Self-efficacy mediates the associations of social support and depression with treatment adherence in heart failure patients. Int J Behav Med. 2013; 20(1):88-96.
21. Macabasco-O’Connell A, DeWalt DA, Broucksou KA, et al. Relationship between literacy, knowledge, self-care behaviors, and heart failure-related quality of life among patients with heart failure. J Gen InternI Med. 2011; 26(9):979-86.
22. Ratanawongsa N, Karter AJ, Parker MM, et al. Communication and medication refill adherence: the Diabetes study of Northern California. JAMA Intern Med. 2013; 173(3):210-8.
23. Fahlberg B. Promoting patient dignity in nursing care. Nursing. 2014; 44(7):14.
24. Baljani MS, Zh. Rahimi MS, Sh. Heidari MS, A. Azimpour MS. The Effect of self-management interventions on medication adherence and life style in cardiovascular patients. Nasim-Danesh. 2013; 20(3):58-68.
25. Heydari A, Ziaee ES, Gazrani A. Relationship between awareness of disease and adherence to therapeutic regimen among cardiac patients. Int J Community Based Nurs Midwifery. 2015; 3(1):23-30.
26. Noureldin M, Plake KS, Morrow DG, Tu W, Wu J, Murray MD. Effect of health literacy on drug adherence in patients with heart failure. Pharmacotherapy. 2012; 32(9):819-26.
27. Dias A, Pereira C, Monteiro MJ, Santos C. Patients’ beliefs about medicines and adherence to medication in ischemic heart disease. Aten Primaria. 2014; 46:101-6.
28. Chochinov HM, Hassard T, McClement S, et al. The patient dignity inventory: a novel way of measuring dignity-related distress in palliative care. J Pain Symptom Manage. 2008; 36(6):559-71.
29. Abbaszadeh A, Borhani F, Rabori R. Patient dignity in coronary care: psychometrics of the Persian version of the patient dignity inventory. British Journal of Medicine and Medical Research. 2015; 8(5):463-9.
30. Morisky DE, Ang A, Krousel‐Wood M, Ward HJ. Predictive validity of a medication adherence measure in an outpatient setting. J Clin Hyperten. 2008; 10(5):348-54
31. Rashedi E, Sohrabi F, Shams J. A study of the efficacy of cognitive behavior therapy in replace prevention of bipolar disorder. Clinical Psychology & Personality. 2011; 2(5):49-64.
32. Alosco ML, Spitznagel MB, van Dulmen M, et al. Cognitive function and treatment adherence in older adults with heart failure. Psychosom Med. 2012; 74(9):965-73.
33. Gehi AK, Ali S, Na B, Whooley MA. Self-reported medication adherence and cardiovascular events in patients with stable coronary heart disease: the heart and soul study. Arch Internal Med. 2007; 167(16):1798-803.
34. van der Wal MH, Jaarsma T, Moser DK, Veeger NJ, van Gilst WH, van Veldhuisen DJ. Compliance in heart failure patients: the importance of knowledge and beliefs. Eur Heart J. 2006; 27(4):434-40.
35. Schweitzer RD, Head K, Dwyer JW. Psychological factors and treatment adherence behavior in patients with chronic heart failure. J Cardiovasc Nurs. 2007; 22(1):76-83.
36. Grenard JL, Munjas BA, Adams JL, et al. Depression and medication adherence in the treatment of chronic diseases in the United States: a meta-analysis. J Gen Intern med. 2011; 26(10):1175-82.
37. Ebrahimzadeh Z, Goodarzi MA, Joulaei H. The Clarification of depression and social support's contribution to the prediction of antiretroviral medication adherence and the rate of CD4 in people with HIV. Glob J Health Sci. 2016; 8(9):54842.
38. Adewuya AO, Afolabi MO, Ola BA, et al. The effect of psychological distress on medication adherence in persons with HIV infection in Nigeria. Psychosomatics. 2010; 51(1):68-73.
39. Chen H-F, Tsai Y-F, Lin Y-P, Shih M-S, Chen J-C. The relationships among medicine symptom distress, self-efficacy, patient–provider relationship, and medication compliance in patients with epilepsy. Epilepsy Behav. 2010; 19(1):43-9.
40. King MLM, Mee LL, Gutiérrez-Colina AM, Eaton CK, Lee JL, Blount RL. Emotional functioning, barriers, and medication adherence in pediatric transplant recipients. J Pediatr Psychol. 2014; 39(3):283-93.
41. Gonzalez JS, Shreck E, Psaros C, Safren SA. Distress and type 2 diabetes-treatment adherence: a mediating role for perceived control. Health Psychol. 2015; 34(5):505.
42. Senior V, Marteau TM, Weinman J. Self-reported adherence to cholesterol-lowering medication in patients with familial hypercholesterolaemia: the role of illness perceptions. Cardiovasc Drugs Ther. 2004; 18(6):475-81.
43. Kretchy I, Owusu-Daaku F, Danquah S. Spiritual and religious beliefs: do they matter in the medication adherence behaviour of hypertensive patients? Biopsychosoc Med. 2013; 7(1):15.
44. Criswell TJ, Weber CA, Xu Y, Carter BL. Effect of self‐efficacy and social support on adherence to antihypertensive drugs. Pharmacotherapy. 2010; 30(5):432-41.
45. Gonzalez JS, Penedo FJ, Antoni MH, et al. Social support, positive states of mind, and HIV treatment adherence in men and women living with HIV/AIDS. Health Psychol. 2004; 23(4):413.
46. Rueda S, Park‐Wyllie LY, Bayoumi A, et al. Patient support and education for promoting adherence to highly active antiretroviral therapy for HIV/AIDS. Cochrane Database Syst Rev. 2006; 12(4):325-34.
47. Edwards LV. Perceived social support and HIV/AIDS medication adherence among African American women. Qual Health Res. 2006; 16(5):679-91.
48. Simoni JM, Frick PA, Huang B. A longitudinal evaluation of a social support model of medication adherence among HIV-positive men and women on antiretroviral therapy. Health Psychol. 2006; 25(1):74-81.
49. Scheurer D, Choudhry N, Swanton KA, Matlin O, Shrank W. Association between different types of social support and medication adherence. Am J Manag Care. 2012; 18(12):e461-7.
50. Wu J-R, Moser DK, Lennie TA, Burkhart PV. Medication adherence in patients who have heart failure: a review of the literature. Nurs Clin North Am. 2008; 43(1):133-53.
51. Sayers SL, Riegel B, Pawlowski S, Coyne JC, Samaha FF. Social support and self-care of patients with heart failure. Ann Behav Med. 2008; 35(1):70-9.
52. Takedai T. The association between social support and medication adherence in adults with rheumatoid arthritis [dissertation]. Pittsburgh (USA). University of Pittsburgh; 2016.
53. Vyavaharkar M, Moneyham L, Tavakoli A, et al. Social support, coping, and medication adherence among HIV-positive women with depression living in rural areas of the southeastern United States. AIDS Patient Care a STDS. 2007; 21(9):667-80.
54. Beals K, Wight R, Aneshensel C, Murphy D, Miller-Martinez D. The role of family caregivers in HIV medication adherence. AIDS care. 2006; 18(6):589-96.
55. Stilley CS, Bender CM, Dunbar-Jacob J, Sereika S, Ryan CM. The impact of cognitive function on medication management: three studies. Health Psychol. 2010; 29(1):50-5.
| Files | ||
| Issue | Vol 10 (2017) | |
| Section | Original Article(s) | |
| Keywords | ||
| Human dignity Medication adherence Heart failure Nursing | ||
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How to Cite
1.
amininasab SS, Azimi lolaty H, Moosazadeh M, Shafipour V. The relationship between human dignity and medication adherence in patients with heart failure. J Med Ethics Hist Med. 2017;10.
