Ethical considerations and challenges associated with euthanasia in laboratory animal research
Abstract
----
Dominguez-Oliva A, Hernández-Avalos I, MartInez-Burnes J, Olmos-Hernandez A, Verduzco-Mendoza A, Mota-Rojas D. The Importance of Animal Models in Biomedical Research: Current Insights and Applications. Animals. 2023;13(7).
Hidayat R, Wulandari P. Euthanasia procedure of animal model in biomedical research. Med J Biomed Transl Res. 2021;5(6):540-4.
Guide for the care and use of laboratory animals; 2010.
Ripplinger EN, Crespo R, Pullin AN, Carnaccini S, Nelson NC, Trindade PHE, et al. Efficacy of a novel cervical dislocation tool for humane euthanasia of broilers and broiler breeders. Poult Sci. 2024;103(3):103449.
Cooney K, Kipperman B. Ethical and Practical Considerations Associated with Companion Animal Euthanasia. Animals. 2023;13(3).
Laferriere CA, Pang DS. Review of intraperitoneal injection of sodium pentobarbital as a method of euthanasia in laboratory rodents. J Am Assoc Lab Anim Sci. 2020;59(3):254-63.
Domínguez-Oliva A, Hernández-Ávalos I, Olmos-Hernández A, Villegas-Juache J, Verduzco-Mendoza A, Mota-Rojas D. Thermal response of laboratory rats (Rattus norvegicus) during the application of six methods of euthanasia assessed by infrared thermography. Animals. 2023;13(18):2820.
Laboratory biosecurity guidance: World Health Organization; 2024.
Clarkson JM, Martin JE, McKeegan DEF. A review of methods used to kill laboratory rodents: issues and opportunities. Lab Anim. 2022;56(5):419-36.
Hickman DL, Johnson SW. Evaluation of the aesthetics of physical methods of euthanasia of anesthetized rats. J Am Assoc Lab Anim Sci. 2011;50(5):695-701.
Kiani AK, Pheby D, Henehan G, Brown R, Sieving P, Sykora P, et al. Ethical considerations regarding animal experimentation. J Prev Med Hyg. 2022;63(2 Suppl 3):E255-E66.
van Rijn CM, Krijnen H, Menting-Hermeling S, Coenen AM. Decapitation in rats: latency to unconsciousness and the 'wave of death'. PloS one. 2011;6(1):e16514.
Balcombe J. Animal pleasure and its moral significance. Appl Anim Behav Sci. 2009;118(3):208-16.
Bailey J. Does the stress of laboratory life and experimentation on animals adversely affect research data? A critical review. Altern Lab Anim. 2018;46(5):291-305.
Carpenter CB. Safety considerations for working with animal models involving human health hazards. Anim Model Exp Med. 2018;1(2):91-9.
Newsome JT, Clemmons EA, Fitzhugh DC, Gluckman TL, Creamer-Hente MA, Tambrallo LJ, et al. Compassion Fatigue, Euthanasia Stress, and Their Management in Laboratory Animal Research. J Am Assoc Lab Anim Sci. 2019;58(3):289-92.
Ahmadi-Noorbakhsh S, Mirabzadeh Ardakani E, Sadighi J, Aldavood SJ, Farajli Abbasi M, Farzad-Mohajeri S, et al. Guideline for the Care and Use of Laboratory Animals in Iran. Lab Anim. 2021;50(11):303-5.
Massoomi MR, Handberg EM. Increasing and Evolving Role of Smart Devices in Modern Medicine. Eur Cardiol. 2019;14(3):181-6.
Files | ||
Issue | Vol 17 (2024) | |
Section | Commentary | |
Keywords | ||
Euthanasia; Laboratory animal; Research ethics; Ethical considerations. |
Rights and permissions | |
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. |